The fastest quarter mile time for a Cadillac CTS-V is held by “The Vette Doctors” with a 10.32 second run at 136.72 mph! Previously owned by the Hennessey CTS-V, will we get to see a grudge match between the two super powers? Only time will tell. Read more about the fastest Cadillac CTS-V in the USA at Tampa Sports Car Examiner.